![]() Accurate estimation of the prevalence of post-stroke cognitive impairment is limited by these and other factors with frequencies varying from 30 to 50%. Īlthough the prevalence of post-stroke cognitive impairment has been studied in different countries, data are inconsistent due to differences in patient characteristics, neuro-psychological assessments, sample sizes, and analytical methods. Cognitive impairment can have an important impact on quality of life and activities of daily living by reducing independence and is associated with long-term morbidity and disability. Persons with mild cognitive impairment (MCI) convert to Alzheimer’s disease (AD) at an annual rate of 10–12% in contrast to 1–2% in the elderly population without MCI. Post-stroke cognitive impairment characteristically involves multiple domains including attention and concentration, executive function, language, memory, and visuospatial function, with executive function being affected the greatest. Up to 64% of stroke survivors develop some degree of cognitive impairment and about 30% die with complications from dementia. Stroke is also the second most common cause of cognitive impairment with stroke survivors often having profound cognitive deficits. Stroke is a major cause of death and disability among adults worldwide, but particularly in low- and middle-income countries in sub-Saharan Africa. Our findings highlight the high burden and need for awareness of cognitive impairment in post stroke populations in the sub-Saharan region and serve to emphasize the importance of detailed cognitive assessment as part of routine clinical evaluation of patients who have had a stroke. The overall mean MoCA score was 11.7-points (range 0.0–28.0-points) for 128 patients with available data of whom 66.4% were categorized as cognitively impaired (MoCA < 19-points). Stepwise multiple logistic regression was used to identify variables independently associated with cognitive impairment. The Montreal Cognitive Assessment (MoCA) was used to assess participants’ cognitive function. ![]() Stroke impairments, disability, and handicap were assessed using the National Institute of Health Stroke Scale (NIHSS), Barthel Index (BI), and modified Rankin scale (mRS), respectively. Independent predictor variables associated with cognitive impairment were ascertained. A questionnaire, clinical examination findings, and laboratory test results were used to collect demographic information and data on vascular risk factors and clinical characteristics. Methodsġ31 patients were enrolled a minimum of 3-months after hospital admission for stroke. The objective of this study was to determine the frequencies, patterns, and risk factors for cognitive impairment in a cross-sectional study of consecutive stroke patients cared for at Uganda’s Mulago Hospital, located in sub-Saharan Africa. Little is known about the characteristics and determinants of post-stroke cognitive impairment in residents of low- and middle-income countries. ![]()
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